Leucine-rich repeat-containing protein 7

Definition:

Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression.

References:

[1]. Ichiro Izawa, et al. Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses. J Biol Chem. 2002 Feb 15;277(7):5345-50. [Content Brief]

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