Low affinity immunoglobulin gamma Fc region receptor II-a

Definition:

Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

References:

[1]. Jinghua Lu, et al. Structural recognition and functional activation of FcgammaR by innate pentraxins. Nature. 2008 Dec 18;456(7224):989-92. [Content Brief]

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