Lysosomal-associated membrane protein 2A (LAMP2A)

Definition:

Lysosomal-associated membrane protein 2A (LAMP2A) is the Chaperone-mediated autophagy (CMA) receptor, is the main target for CMA regulation, since its level on the lysosomal membrane directly pinpoints the CMA activity at any given time.

References:

[1]. Cuervo AM, Dice JF. Regulation of lamp2a levels in the lysosomal membrane. Traffic. 2000 Jul;1(7):570-83. [Content Brief]

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