Lysosomal-trafficking regulator
Definition:
References:
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[1]. Velizar T Tchernev, et al. The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins. Mol Med. 2002 Jan;8(1):56-64. [Content Brief]
[2]. Fernando E Sepulveda, et al. LYST controls the biogenesis of the endosomal compartment required for secretory lysosome function. Traffic. 2015 Feb;16(2):191-203. [Content Brief]
[3]. Petter Holland, et al. LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis. Traffic. 2014 Dec;15(12):1390-405. [Content Brief]
[4]. Andreas Westphal, et al. Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor-mediated inflammatory responses. J Exp Med. 2017 Jan;214(1):227-244. [Content Brief]
[5]. Aleksandra Gil-Krzewska, et al. Chediak-Higashi syndrome: Lysosomal trafficking regulator domains regulate exocytosis of lytic granules but not cytokine secretion by natural killer cells. J Allergy Clin Immunol. 2016 Apr;137(4):1165-1177. [Content Brief]
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