Membrane primary amine oxidase

Definition:

Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity. May play a role in adipogenesis.

References:

[1]. Sam Kaitaniemi, et al. Functional modulation of vascular adhesion protein-1 by a novel splice variant. PLoS One. 2013;8(1):e54151. [Content Brief]

[2]. D J Smith, et al. Cloning of vascular adhesion protein 1 reveals a novel multifunctional adhesion molecule. J Exp Med. 1998 Jul 6;188(1):17-27. [Content Brief]

[3]. Sam Kaitaniemi, et al. The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase. Cell Mol Life Sci. 2009 Aug;66(16):2743-57. [Content Brief]

[4]. Sandy Bour, et al. Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes. Biochimie. 2007 Aug;89(8):916-25. [Content Brief]

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