Myosin-7
Definition:
Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.
References:
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[1]. Donald A Winkelmann, et al. Structural basis for drug-induced allosteric changes to human β-cardiac myosin motor activity. Nat Commun. 2015 Aug 6;6:7974. [Content Brief]
[2]. Keenan C Taylor, et al. Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3806-15. [Content Brief]
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