2. Biology Dictionary
  3. N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

Definition:

Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N-acetylglucosaminyltransferases.

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