N-acetylneuraminate 9-O-acetyltransferase

Definition:

O-acetyltransferase that catalyzes 9-O-acetylation of sialic acids. Sialic acids are sugars at the reducing end of glycoproteins and glycolipids, and are involved in various processes such as cell-cell interactions, host-pathogen recognition.

References:

[1]. Sigrid Arming, et al. The human Cas1 protein: a sialic acid-specific O-acetyltransferase?. Glycobiology. 2011 May;21(5):553-64. [Content Brief]

[2]. Anna-Maria T Baumann, et al. 9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate. Nat Commun. 2015 Jul 14;6:7673. [Content Brief]

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