Nck-associated protein 5-like
Definition:
Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation.
References:
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[1]. Yusuke Mori, et al. Microtubule-bundling activity of the centrosomal protein, Cep169, and its binding to microtubules. Biochem Biophys Res Commun. 2015 Nov 27;467(4):754-9. [Content Brief]
[2]. Yusuke Mori, et al. Cep169, a Novel Microtubule Plus-End-Tracking Centrosomal Protein, Binds to CDK5RAP2 and Regulates Microtubule Stability. PLoS One. 2015 Oct 20;10(10):e0140968. [Content Brief]
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