Neurobeachin-like protein 2

Definition:

Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis.

References:

[1]. Cornelis A Albers, et al. Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome. Nat Genet. 2011 Jul 17;43(8):735-7. [Content Brief]

[2]. Meral Gunay-Aygun, et al. NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules. Nat Genet. 2011 Jul 17;43(8):732-4. [Content Brief]

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