Neuroserpin
Definition:
References:
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[1]. Stefano Ricagno, et al. Human neuroserpin: structure and time-dependent inhibition. J Mol Biol. 2009 Apr 24;388(1):109-21. [Content Brief]
[2]. Rosina Noto, et al. The stability and activity of human neuroserpin are modulated by a salt bridge that stabilises the reactive centre loop. Sci Rep. 2015 Sep 2;5:13666. [Content Brief]
[3]. T Osterwalder, et al. The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin. J Biol Chem. 1998 Jan 23;273(4):2312-21. [Content Brief]
[4]. Sayaka Takehara, et al. The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability. J Mol Biol. 2009 Apr 24;388(1):11-20. [Content Brief]
[5]. Didier Belorgey, et al. Mutant Neuroserpin (S49P) that causes familial encephalopathy with neuroserpin inclusion bodies is a poor proteinase inhibitor and readily forms polymers in vitro. J Biol Chem. 2002 May 10;277(19):17367-73. [Content Brief]
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