Non-Hodgkin lymphoma

Definition:

Non-Hodgkin lymphoma (NHL) is one of the most common hematologic malignancies worldwide. NHL includes malignant tumors of the lymphoid tissues variously resulting from the clonal growth of B cells, T cells and natural killer cells. NHL can be broadly classified based on the type of lymphocyte involved: B lymphocyte (B cell) or T lymphocyte (T cell) and is further classified by other factors, including whether it is aggressive or indolent. Aggressive NHL is fast-growing disease. It mainly includes mantle cell lymphoma, diffuse large B-cell lymphoma, Burkitt's lymphoma, lymphoblastic lymphoma and peripheral T-cell lymphoma. On the other hand, indolent NHL is slow-growing disease. It mainly includes follicular lymphoma, cutaneous T-cell lymphoma, lymphoplasmacytic lymphoma and MALT lymphoma.

References:

[1]. M Matsuda, et al. Mutations in the RAD54 recombination gene in primary cancers. Oncogene. 1999 Jun 3;18(22):3427-30. [Content Brief]

[2]. Min Sun Shin, et al. Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. Blood. 2002 Jun 1;99(11):4094-9. [Content Brief]

[3]. Rita Clementi, et al. A proportion of patients with lymphoma may harbor mutations of the perforin gene. Blood. 2005 Jun 1;105(11):4424-8. [Content Brief]

[4]. T Hiramoto, et al. Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. Oncogene. 1999 Jun 3;18(22):3422-6. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.