Non-homologous end joining (NHEJ)

Definition:

Non-homologous end joining (NHEJ) is a pathway that repairs DNA double-strand breaks in the cell cycle. NHEJ relies on the Ku protein to thread onto each broken DNA end.

References:

[1]. Chang HHY, et al. Non-homologous DNA end joining and alternative pathways to double-strand break repair. Nat Rev Mol Cell Biol. 2017 Aug;18(8):495-506. [Content Brief]

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