Nuclear receptor subfamily 4 group A member 2

Definition:

Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).

References:

[1]. Kirsten Messmer, et al. Induction of tyrosine hydroxylase expression by the transcription factor Pitx3. Int J Dev Neurosci. 2007 Feb;25(1):29-37. [Content Brief]

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