Olfactory receptor 1D2

Definition:

Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception.

References:

[1]. Marc Spehr, et al. Dual capacity of a human olfactory receptor. Curr Biol. 2004 Oct 5;14(19):R832-3. [Content Brief]

[2]. Eva M Neuhaus, et al. Novel function of beta-arrestin2 in the nucleus of mature spermatozoa. J Cell Sci. 2006 Aug 1;119(Pt 15):3047-56. [Content Brief]

[3]. Marc Spehr, et al. Identification of a testicular odorant receptor mediating human sperm chemotaxis. Science. 2003 Mar 28;299(5615):2054-8. [Content Brief]

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