OTU domain-containing protein 7A

Definition:

Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains.

References:

[1]. Tycho E T Mevissen, et al. OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. Cell. 2013 Jul 3;154(1):169-84. [Content Brief]

[2]. Anja Bremm, et al. Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne. Nat Struct Mol Biol. 2010 Aug;17(8):939-47. [Content Brief]

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