2. Biology Dictionary
  3. Primary myelofibrosis (PMF)

Primary myelofibrosis (PMF)

Definition:

Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by stem cell-derived clonal myeloproliferation, abnormal cytokine expression, bone marrow fibrosis, anemia, splenomegaly, extramedullary hematopoiesis (EMH), constitutional symptoms, cachexia, leukemic progression, and shortened survival.

Biomedical Dictionary

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