Ran guanine nucleotide release factor
Definition:
References:
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[1]. K A Marfatia, et al. Identification and characterization of the human MOG1 gene. Gene. 2001 Mar 21;266(1-2):45-56. [Content Brief]
[2]. Xiaoling Bao, et al. Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation. J Mol Cell Biol. 2018 Feb 1;10(1):18-32. [Content Brief]
[3]. Ling Wu, et al. Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5. J Biol Chem. 2008 Mar 14;283(11):6968-78. [Content Brief]
[4]. Susmita Chakrabarti, et al. MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and sick sinus syndrome. Circ Arrhythm Electrophysiol. 2013 Apr;6(2):392-401. [Content Brief]
[5]. Morten S Olesen, et al. A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias. Can J Cardiol. 2011 Jul-Aug;27(4):523.e17-23. [Content Brief]
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