Ras-related protein R-Ras2

Definition:

GTP-binding protein with GTPase activity involved in the regulation of MAPK signaling pathway, thereby controlling multiple cellular processes. Involved in the regulation of MAPK signaling pathway. Regulation of craniofacial development.

References:

[1]. Tetsuya Niihori, et al. Germline-Activating RRAS2 Mutations Cause Noonan Syndrome. Am J Hum Genet. 2019 Jun 6;104(6):1233-1240. [Content Brief]

[2]. Yline Capri, et al. Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome. Am J Hum Genet. 2019 Jun 6;104(6):1223-1232. [Content Brief]

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