Receptor-interacting protein kinases (RIPKs)

Definition:

Receptor-interacting protein kinases (RIPKs) are serine/threonine kinases that assemble multi-molecular complexes that induce apoptosis, necroptosis, inflammasome and nuclear factor kappa B activation.

References:

[1]. Wu L, et al. Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis. Cell Death Dis. 2021 Nov 9;12(11):1064. [Content Brief]

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