Receptor-transporting protein 4

Definition:

Probable chaperone protein which facilitates trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional expression of the bitter taste receptor TAS2R16. Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1 (By similarity).

References:

[1]. Maik Behrens, et al. Members of RTP and REEP gene families influence functional bitter taste receptor expression. J Biol Chem. 2006 Jul 21;281(29):20650-9. [Content Brief]

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