Selenoprotein N
Definition:
References:
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[1]. Sandrine Arbogast, et al. Oxidative stress in SEPN1-related myopathy: from pathophysiology to treatment. Ann Neurol. 2009 Jun;65(6):677-86. [Content Brief]
[2]. Perrine Castets, et al. Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency. Hum Mol Genet. 2011 Feb 15;20(4):694-704. [Content Brief]
[3]. Michael J Jurynec, et al. Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12485-90. [Content Brief]
[4]. Marianna Marino, et al. SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity. Hum Mol Genet. 2015 Apr 1;24(7):1843-55. [Content Brief]
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