Septin-11

Definition:

Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.

References:

[1]. Serge Mostowy, et al. Septin 11 restricts InlB-mediated invasion by Listeria. J Biol Chem. 2009 Apr 24;284(17):11613-21. [Content Brief]

[2]. Nobuhiro Hanai, et al. Biochemical and cell biological characterization of a mammalian septin, Sept11. FEBS Lett. 2004 Jun 18;568(1-3):83-8. [Content Brief]

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