Serine--tRNA ligase, cytoplasmic
Definition:
References:
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[1]. Yi Shi, et al. tRNA synthetase counteracts c-Myc to develop functional vasculature. Elife. 2014 Jun 17;3:e02349. [Content Brief]
[2]. Hajime Fukui, et al. Noncanonical activity of seryl-tRNA synthetase is involved in vascular development. Circ Res. 2009 Jun 5;104(11):1253-9. [Content Brief]
[3]. Xiaoling Xu, et al. Unique domain appended to vertebrate tRNA synthetase is essential for vascular development. Nat Commun. 2012 Feb 21;3:681. [Content Brief]
[4]. Wiebke Herzog, et al. Genetic evidence for a noncanonical function of seryl-tRNA synthetase in vascular development. Circ Res. 2009 Jun 5;104(11):1260-6. [Content Brief]
[5]. C Vincent, et al. Genomic organization, cDNA sequence, bacterial expression, and purification of human seryl-tRNA synthase. Eur J Biochem. 1997 Nov 15;250(1):77-84. [Content Brief]
[6]. Caiyan Wang, et al. SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis. Nucleic Acids Res. 2015 Dec 2;43(21):10534-45. [Content Brief]
[7]. Xiaoling Xu, et al. Crystal structure of human Seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes. Structure. 2013 Nov 5;21(11):2078-86. [Content Brief]
[8]. Luciana Musante, et al. Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability. Hum Mutat. 2017 Jun;38(6):621-636. [Content Brief]
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