Sodium- and chloride-dependent GABA transporter 2

Definition:

Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA). Mediates transport of beta-alanine. Can also mediate transport of taurine and hypotaurine (By similarity).

References:

[1]. Bolette Christiansen, et al. Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2. J Biol Chem. 2007 Jul 6;282(27):19331-41. [Content Brief]

[2]. Avner Schlessinger, et al. High selectivity of the γ-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach. J Biol Chem. 2012 Nov 2;287(45):37745-56. [Content Brief]

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