Up-regulator of cell proliferation

Definition:

May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer.

References:

[1]. Jiugang Song, et al. Enhanced cell survival of gastric cancer cells by a novel gene URG4. Neoplasia. 2006 Dec;8(12):995-1002. [Content Brief]

[2]. N Lale Satiroglu Tufan, et al. Hepatitis Bx antigen stimulates expression of a novel cellular gene, URG4, that promotes hepatocellular growth and survival. Neoplasia. 2002 Jul-Aug;4(4):355-68. [Content Brief]

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