Vesicular, overexpressed in cancer, prosurvival protein 1

Definition:

Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.

References:

[1]. S Park, et al. ECop (EGFR-coamplified and overexpressed protein), a novel protein, regulates NF-kappaB transcriptional activity and associated apoptotic response in an IkappaBalpha-dependent manner. Oncogene. 2005 Apr 7;24(15):2495-502. [Content Brief]

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