Zinc finger CCCH domain-containing protein 15

Definition:

Protects DRG1 from proteolytic degradation. Stimulates DRG1 GTPase activity likely by increasing the affinity for the potassium ions.

References:

[1]. Isabel Pérez-Arellano, et al. Human Drg1 is a potassium-dependent GTPase enhanced by Lerepo4. FEBS J. 2013 Aug;280(15):3647-57. [Content Brief]

[2]. Kosuke Ishikawa, et al. Independent stabilizations of polysomal Drg1/Dfrp1 complex and non-polysomal Drg2/Dfrp2 complex in mammalian cells. Biochem Biophys Res Commun. 2009 Dec 18;390(3):552-6. [Content Brief]

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