ALDH1B1 - aldehyde dehydrogenase 1 family member B1 Gene

Also Known as ALDH5; ALDHX

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 219

About ALDH1B1

Cytogenetic location: 9p13.1 Genomic coordinates (GRCh38): 9:38,392,702-38,398,661 (from NCBI)

This gene has 2 transcripts (splice variants), 290 orthologues and 17 paralogues. Broad expression in liver (RPKM 58.4), kidney (RPKM 38.9) and 19 other tissues.

Summary

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]

ALDH1B1 Products (1)

mRNA Protein Name
NM_000692.5 NP_000683.3 aldehyde dehydrogenase X, mitochondrial precursor

ALDH1B1 Protein Structure

Aldedh

Aldedh: Aldehyde dehydrogenase family (45 - 508)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 517 a.a.
Protein Preferred Names Protein Names

aldehyde dehydrogenase X, mitochondrial

  • ALDH class 2

ALDH1B1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810845 ALDH1B1 Antibody WB, IHC-P Human, Mouse, Rat

Related Diseases

Diseases Alias
Gamma-Amino Butyric Acid Metabolism Disorder

  • Disorder Of Gamma-Aminobutyric Acid Metabolism

  • Disorder Of Gaba Metabolism

  • Disorders Of Gaba - [Gamma Aminobutyric Acid] Metabolism
Succinic Semialdehyde Dehydrogenase Deficiency

  • 4-Hydroxybutyric Aciduria

  • Ssadh Deficiency

  • Gamma-Hydroxybutyric Aciduria

  • Gaba Metabolic Defect

  • SSADHD

  • Ssadh

  • Succinate-Semialdehyde Dehydrogenase Deficiency

  • Gamma-Hydroxybutyricaciduria

  • 4-Hydroxybutyricaciduria

  • Gamma-Hydroxybutyric Acidemia

  • Succinate Semialdehyde Dehydrogenase Deficiency
Hyperprolinemia

  • Proline Oxidase Deficiency

  • Hyperprolinemia Type 1

  • Proline Hydrogenase Deficiency

  • Prolinemia

  • Pyrroline Carboxylate Dehydrogenase Deficiency

  • Pyrroline-5-Carboxylate Dehydrogenase Deficiency

  • Proline Dehydrogenase Deficiency

  • Hyperprolinemia Type 2
Sjogren-Larsson Syndrome

  • Sjögren-Larsson Syndrome

  • SLS

  • Faldh Deficiency

  • Fatty Aldehyde Dehydrogenase Deficiency

  • Fatty Acid Alcohol Oxidoreductase Deficiency

  • Ichthyosis, Spastic Neurologic Disorder, And Oligophrenia

  • Sjogren Larsson Syndrome

  • Fatty Alcohol:Nad+ Oxidoreductase Deficiency

  • Sjogren-Larsson'S Syndrome

  • Fadh Deficiency

  • Fao Deficiency

  • Congenital Icthyosis Mental Retardation Spasticity Syndrome

  • Ichthyosis Oligophrenia Syndrome

  • Sjoegren-Larsson Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-125085 ALDH3A1-IN-3 Inhibitor 99.43% Unkown
HY-148466 IGUANA-1 Inhibitor 98.93% Unkown
HY-148243 IGUANA-1 free base Inhibitor 99.69% Unkown
HY-128299 ALDH3A1-IN-4 Inhibitor 99.91% Unkown
HY-RS00565 ALDH1B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17566 Aldh1b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24026 Aldh1b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ALDH1B1 VGNC VGNC:81354
Rattus norvegicus ALDH1B1 RGD RGD:1306737
Mus musculus ALDH1B1 MGD MGI:1919785
Felis catus ALDH1B1 VGNC VGNC:102898
Bos taurus ALDH1B1 VGNC VGNC:25810
Canis familiaris ALDH1B1 VGNC VGNC:51696
Others ALDH1B1 NCBI