WBP1 - WW domain binding protein 1 Gene

Also Known as WBP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23559

About WBP1

Cytogenetic location: 2p13.1 Genomic coordinates (GRCh38): 2:74,458,438-74,460,881 (from NCBI)

This gene has 14 transcripts (splice variants), 240 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 48.7), prostate (RPKM 45.8) and 25 other tissues.

Summary

The globular WW domain, named for the conserved tryptophan residues in the protein motif present in various structural and regulatory proteins, is known to play a role in the mediation of protein-protein interactions. This gene encodes a ligand of the WW domain of the Yes kinase-associated protein. Readthrough transcription of the neighboring upstream gene, which encodes INO80 complex subunit B, into this gene generates a non-coding transcript. [provided by RefSeq, Feb 2011]

WBP1 Products (1)

mRNA Protein Name
NM_012477.4 NP_036609.1 WW domain-binding protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables WW domain binding IPI
IPI: Inferred from physical interaction
15064722 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
15064722 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WBP1 Protein Structure

WBP-1

WBP-1: WW domain-binding protein 1 (36 - 142)

  • 0
  • 100
  • 200
  • 269 a.a.
Protein Preferred Names Protein Names

WW domain-binding protein 1

  • epididymis secretory sperm binding protein

WBP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
WBP1 Q96G27 YAP1 Homo sapiens P46937
ITC
25283809
Intra
WBP1 Q96G27 EPN2 Homo sapiens O95208-2
Y2H Array
32296183
Intra
WBP1 Q96G27 EPN2 Homo sapiens O95208-2
Y2H Prey Pooling
32296183
Intra
WBP1 Q96G27 WWOX Homo sapiens Q9NZC7
Far-WB
15064722
Intra
WBP1 Q96G27 WWOX Homo sapiens Q9NZC7
Anti Tag CoIP
33961781
Intra
WBP1 Q96G27 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant WBP1 Proteins

Cat. No. Product Name Accession Purity
HY-P71430 WBP1 Protein, Human (His) Q96G27 (G170-P269) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03619 DDOST Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15748 WBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-178040 Insecticidal agent 26 Inhibitor / Unkown
HY-RS22358 Wbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28880 Wbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta WBP1 VGNC VGNC:78785
Rattus norvegicus WBP1 RGD RGD:1304961
Bos taurus WBP1 VGNC VGNC:36870
Canis familiaris WBP1 VGNC VGNC:48338
Felis catus WBP1 VGNC VGNC:81258
Mus musculus WBP1 MGD MGI:104710
Others WBP1 NCBI