2. Gene
  3. RNPEP - arginyl aminopeptidase Gene

RNPEP - arginyl aminopeptidase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as APB; AP-B

Gene ID: 6051 | Gene type: protein coding

About RNPEP

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:201,982,648-202,006,143 (from NCBI)

This gene has 14 transcripts (splice variants), 156 orthologues and 11 paralogues. Ubiquitous expression in duodenum (RPKM 31.1), colon (RPKM 27.9) and 25 other tissues.

Summary

Predicted to enable metalloaminopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

RNPEP Products(4)

mRNA Protein Name
NM_001319184.2 NP_001306113.1 aminopeptidase B isoform c
NM_001319183.2 NP_001306112.1 aminopeptidase B isoform c
NM_020216.4 NP_064601.3 aminopeptidase B isoform a
NM_001319182.2 NP_001306111.1 aminopeptidase B isoform b precursor

RNPEP Protein Structure

Peptidase_M1

Peptidase_M1: Peptidase family M1 domain (36 - 417)

Leuk-A4-hydro_C

Leuk-A4-hydro_C: Leukotriene A4 hydrolase, C-terminal (500 - 644)

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  • 650 a.a.
Protein Preferred Names Protein Names

aminopeptidase B

arginine aminopeptidase

Related Diseases

Diseases Alias
Histrionic Personality Disorder
Subacute Bacterial Endocarditis

Endocarditis Lenta

Sbe - Subacute Bacterial Endocarditis

Subacute Endocarditis, Lenta

Endocarditis, Subacute Bacterial
Haverhill Fever

Streptobacillosis

Streptobacillary Rat-Bite Fever

Streptobacillary Fever

Rat-Bite Fever Due To Streptobacillus Moniliformis

Erythema Arthriticum Epidemicum

Epidemic Arthritic Erythema
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12104 RNPEP Human Pre-designed siRNA Set A / Unkown
HY-RS12105 Rnpep Mouse Pre-designed siRNA Set A / Unkown
HY-RS12106 Rnpep Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RNPEP VGNC VGNC:58406
Mus musculus RNPEP MGD MGI:2384902
Macaca mulatta RNPEP VGNC VGNC:76711
Rattus norvegicus RNPEP RGD RGD:621137
Canis familiaris RNPEP VGNC VGNC:45682
Felis catus RNPEP VGNC VGNC:64711