TCF15 - transcription factor 15 Gene

Also Known as EC2; PARAXIS; bHLHa40

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6939

About TCF15

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:604,257-610,309 (from NCBI)

This gene has 1 transcript (splice variant), 241 orthologues and 13 paralogues. Biased expression in fat (RPKM 5.9), heart (RPKM 2.3) and 3 other tissues.

Summary

The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]

TCF15 Products (1)

mRNA Protein Name
NM_004609.4 NP_004600.3 transcription factor 15

TCF15 Protein Structure

HLH

HLH: Helix-loop-helix DNA-binding domain (73 - 124)

  • 0
  • 100
  • 199 a.a.
Protein Preferred Names Protein Names

transcription factor 15

  • TCF-15

Related Diseases

Diseases Alias
Elsahy-Waters Syndrome

  • Brachioskeletogenital Syndrome

  • Bsg Syndrome

  • Branchioskeletogenital Syndrome

  • ESWS

  • Hypospadias, Hypertelorism, Upper Lid Coloboma, And Mixed-Type Hearing Loss

  • Branchio-Skeleto-Genital Syndrome
Diffuse Gastric And Lobular Breast Cancer Syndrome

  • Hereditary Diffuse Gastric Cancer

  • HDGC

  • LBC

  • Familial Diffuse Gastric Cancer

  • Fdgc

  • Hereditary Diffuse Gastric Adenocarcinoma

  • Breast Cancer, Lobular

  • Gastric Cancer, Familial Diffuse, And Cleft Lip With Or Without Cleft Palate

  • DGLBC

  • Gastric Cancer, Hereditary Diffuse

  • Gastric Cancer, Familial Diffuse Breast Cancer, Lobular

  • Diffuse Gastric And Lobular Breast Cancer Syndrome With Or Without Cleft Lip And/Or Palate

  • E-Cadherin-Associated Hereditary Gastric Cancer

  • Familial Diffuse Cancer Of Stomach

  • Hereditary Diffuse Cancer Of Stomach

  • Gastric Cancer Familial Diffuse

  • Gastric Cancer Familial Diffuse And Cleft Lip With Or Without Cleft Palate

  • Cancer, Gastric, Hereditary Diffuse
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14300 TCF15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TCF15 VGNC VGNC:47190
Rattus norvegicus TCF15 RGD RGD:1308464
Mus musculus TCF15 MGD MGI:104664
Bos taurus TCF15 VGNC VGNC:35687
Macaca mulatta TCF15 VGNC VGNC:78284
Others TCF15 NCBI