TCF15 - transcription factor 15 Gene

Homo sapiens

Also known as EC2; PARAXIS; bHLHa40

Gene ID: 6939 | Gene type: protein coding

About TCF15

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:604,257-610,309 (from NCBI)

This gene has 1 transcript (splice variant), 241 orthologues and 13 paralogues. Biased expression in fat (RPKM 5.9), heart (RPKM 2.3) and 3 other tissues.

Summary

The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]

TCF15 Products(1)

mRNA	Protein	Name
NM_004609.4	NP_004600.3	transcription factor 15

TCF15 Protein Structure

HLH

0
100
199 a.a.

Protein Preferred Names

Protein Names

transcription factor 15

TCF-15

Related Diseases

Diseases

Alias

Elsahy-Waters Syndrome

Brachioskeletogenital Syndrome	Bsg Syndrome
Branchioskeletogenital Syndrome	ESWS
Hypospadias, Hypertelorism, Upper Lid Coloboma, And Mixed-Type Hearing Loss	Branchio-Skeleto-Genital Syndrome

Diffuse Gastric And Lobular Breast Cancer Syndrome

Hereditary Diffuse Gastric Cancer	HDGC
LBC	Familial Diffuse Gastric Cancer
Fdgc	Hereditary Diffuse Gastric Adenocarcinoma
Breast Cancer, Lobular	Gastric Cancer, Familial Diffuse, And Cleft Lip With Or Without Cleft Palate
DGLBC	Gastric Cancer, Hereditary Diffuse
Gastric Cancer, Familial Diffuse Breast Cancer, Lobular	Diffuse Gastric And Lobular Breast Cancer Syndrome With Or Without Cleft Lip And/Or Palate
E-Cadherin-Associated Hereditary Gastric Cancer	Familial Diffuse Cancer Of Stomach
Hereditary Diffuse Cancer Of Stomach	Gastric Cancer Familial Diffuse
Gastric Cancer Familial Diffuse And Cleft Lip With Or Without Cleft Palate	Cancer, Gastric, Hereditary Diffuse

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14300	TCF15 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TCF15	VGNC	VGNC:47190
Rattus norvegicus	TCF15	RGD	RGD:1308464
Mus musculus	TCF15	MGD	MGI:104664
Bos taurus	TCF15	VGNC	VGNC:35687
Macaca mulatta	TCF15	VGNC	VGNC:78284

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