2. Peptides
  3. HBpep-SA

HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

HBpep-SA Chemical Structure

HBpep-SA Chemical Structure

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HBpep-SA Related Antibodies

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Description

HBpep-SA is a cell membrane-permeable peptide condensate that phase separates to form stable droplets at pH values below 6.5. HBpep-SA is able to directly and efficiently deliver a variety of macromolecules, ranging from therapeutic peptides as small as 726 Da to large enzymes as large as 430 kDa, and the loaded condensates remain stable under near-physiological and serum conditions until internalized by cells. HBpep-SA can be used for intracellular delivery of large numbers of macromolecules and as a vector for mRNA-based vaccines[1].

Molecular Weight

3132.41

Formula

C145H187N39O37S2
Sequence

Gly-His-Gly-Val-Tyr-Gly-His-Gly-Val-Tyr-Gly-His-Gly-Pro-Tyr-{Lys(NHS-SS-Ac)}-Gly-His-Gly-Pro-Tyr-Gly-His-Gly-Leu-Tyr-Trp
Sequence Shortening

GHGVYGHGVYGHGPY-{Lys(NHS-SS-Ac)}-GHGPYGHGLYW
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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The dilution calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HBpep-SAOthersmRNApeptidedropletdeliveryInhibitorinhibitorinhibit

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