2. Academic Validation
  3. Total synthesis of adicardin

Total synthesis of adicardin

  • J Asian Nat Prod Res. 2009 Aug;11(8):720-7. doi: 10.1080/10286020903042341.
Wei Li 1,  Xiao-Feng Wu,  Yuan-Feng Tong,  Ling-Hua Hao,  Qing-Yun Yang,  Yan Qi,  Song Wu
Affiliations

Affiliation

  • 1 Department of New Drug Research and Development, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College (Key Laboratory of Biosynthesis of Natural Products, Ministry of Health of PRC), Beijing, China.
PMID: 20183314 DOI: 10.1080/10286020903042341
Abstract

The first synthesis of adicardin, a compound with anti-chronic renal failure activity isolated from Hydrangea macrophylla, has been described. The structures of the target compound and intermediates have been validated by MS, NMR, and identical with the natural product.

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