2. Academic Validation
  3. Effect of quercetin-3-O-sambubioside isolated from Eucommia ulmoides male flowers on spontaneous activity and convulsion rate in mice

Effect of quercetin-3-O-sambubioside isolated from Eucommia ulmoides male flowers on spontaneous activity and convulsion rate in mice

  • Planta Med. 2014 Aug;80(12):974-7. doi: 10.1055/s-0034-1382902.
Xin Li 1,  Lipeng Yang 1,  Shaoyang Liu 2,  Dongqing Fei 3,  Min Zhang 1,  Yuxian Zhang 1
Affiliations

Affiliations

  • 1 College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
  • 2 Food Engineering Department, Luohe Medical College, Luohe, China.
  • 3 School of Pharmacy, Lanzhou University, Lanzhou, China.
PMID: 25098932 DOI: 10.1055/s-0034-1382902
Abstract

The purpose of this study was to evaluate the effects of quercetin-3-O-sambubioside on the neural system. Quercetin-3-O-sambubioside is a monomeric compound found in Eucommia ulmoides male flowers from which it was extracted using a system solvent method. In the experiments, spontaneous activity and convulsion rate in mice were recorded, and quercetin-3-O-sambubioside shows eminent effects similar to nikethamide on increasing spontaneous activity and stimulating the nerve center to enhance excitement. These findings are indicative of the powerful ability of quercetin-3-O-sambubioside to promote the stimulation of the nerve center.

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