2. Academic Validation
  3. The genetics of Ménière's disease

The genetics of Ménière's disease

  • Appl Clin Genet. 2015 Jan 8;8:9-17. doi: 10.2147/TACG.S59024.
Giuseppe Chiarella 1,  C Petrolo 1,  E Cassandro 2
Affiliations

Affiliations

  • 1 Department of experimental and Clinical Medicine, Audiology and Phoniatrics Unit, Magna Graecia University of Catanzaro, Catanzaro, Italy.
  • 2 Department of Medicine and Surgery, University of Salerno, Salerno, Italy.
PMID: 25609993 DOI: 10.2147/TACG.S59024
Abstract

Our understanding of the genetic basis of Ménière's disease (MD) is still limited. Although the familial clustering and the geographical and racial differences in incidence strongly suggest a certain role for genetic factors in the development of MD, no convincing evidence for an association with any gene exists, at present. In this review, starting from rational bases for a genetic approach to MD, we explored the numerous reports published in literature and summarize the recent advances in understanding of the genetic fundaments of the disease.

Keywords

Mènière’s disease; etiology; gene; pathogenesis; vertigo.

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