2. Academic Validation
  3. Shoshin Beriberi in Critically-Ill patients: case series

Shoshin Beriberi in Critically-Ill patients: case series

  • Nutr J. 2015 May 17;14:51. doi: 10.1186/s12937-015-0039-7.
George Dabar 1,  Carine Harmouche 2,  Bassem Habr 3,  Moussa Riachi 4,  Bertrand Jaber 5
Affiliations

Affiliations

  • 1 Pulmonary and critical section, Hotel Dieu de France Hospital, Saint Joseph University School of Medicine, 16-16830, Beirut, Lebanon. [email protected].
  • 2 Pulmonary and critical section, Hotel Dieu de France Hospital, Saint Joseph University School of Medicine, 16-16830, Beirut, Lebanon. [email protected].
  • 3 Pulmonary and critical section, Hotel Dieu de France Hospital, Saint Joseph University School of Medicine, 16-16830, Beirut, Lebanon. [email protected].
  • 4 Pulmonary and critical section, Hotel Dieu de France Hospital, Saint Joseph University School of Medicine, 16-16830, Beirut, Lebanon. [email protected].
  • 5 Department of Medicine, Kidney and Dialysis Research Laboratory, Division of Nephrology, St. Elizabeth's Medical Center, 736 Cambridge Street, 02135, Boston, MA, USA. [email protected].
PMID: 25982313 DOI: 10.1186/s12937-015-0039-7
Abstract

Thiamine plays a fundamental role in cellular metabolism. The classical syndrome caused by thiamine deficiency is beriberi, and its fulminant variant, once considered an uncommon finding, is now encountered among the critically ill.We present a case series of four critically ill non-septic non-alcoholic patients with severe lactic acidosis and refractory cardio-circulatory collapse caused by acute fulminant beriberi, which drastically responded to thiamine administration.In critical care settings, increased awareness of this life-threatening but reversible condition is a requirement, especially among patients receiving parenteral nutrition and those with unexplained recalcitrant lactic acidosis.

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