1. Academic Validation
  2. [Chemical constituents from lipophilic parts in roots of Angelica dahurica cv.Yubaizhi]

[Chemical constituents from lipophilic parts in roots of Angelica dahurica cv.Yubaizhi]

  • Zhongguo Zhong Yao Za Zhi. 2017 Jun;42(11):2102-2109. doi: 10.19540/j.cnki.cjcmm.20170223.023.
Gai-Gai Deng 1 Xiu-Wei Yang 1 You-Bo Zhang 1 Wei Xu 1 Wei Wei 1 Zhen-Guo Li 2
Affiliations

Affiliations

  • 1 State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • 2 Henan Provincial Institute of Food and Drug Control, Zhengzhou 450008, China.
Abstract

The chemical constituents from lipophilic parts in the roots of Angelica dahurica cv. Yubaizhi were studied in this paper. The compounds were separated and purified by repeated column chromatographic methods on silica gel and HPLC, and the chemical structures of compounds were determined by spectral data analyses. Thirty-three compounds were obtained and identified as isoimperatorin (1), imperatorin (2), stigmasterol (3), isooxypeucedanin (4), pabulenol (5), psoralen (6), bergapten (7), isodemethylfuropinarine (8), phellopterin (9), osthenol (10), alloimperatorin (11), xanthotoxin (12), xanthotoxol (13), isopimpinellin (14), alloisoimperatorin (15), β-sitosterol (16), oxyalloimperatorin (17), pabularinone (18), 5-hydroxy-8-methoxypsoralen (19), columbianetin (20), heracol (21), isogosferol (22), 2″R-neobyakangelicol (23), byakangelicin ethoxide (24), byakangelicin (25), oxypeucedanin hydrate (26), uracil (27), umbelliferone (28), bergaptol (29), demethylfuropinarine (30), isobyakangelicol (31), oxypeucedanin ethanolate (32), heraclenol (33). Among them, compounds 8, 10, 17, 21, and 30 were obtained from the roots of title plant for the first time.

Keywords

Angelica dahurica cv. Yubaizhi; coumarins; demethylfuropinarine; heracol; isodemethylfuropinarine; osthenol; oxyalloimperatorin.

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