2. Academic Validation
  3. New anthracene and anthraquinone metabolites from Prismatomeris filamentosa and their antibacterial activities

New anthracene and anthraquinone metabolites from Prismatomeris filamentosa and their antibacterial activities

  • Nat Prod Res. 2021 May;35(10):1582-1589. doi: 10.1080/14786419.2019.1627352.
Awat Wisetsai 1,  Ratsami Lekphrom 1,  Florian T Schevenels 1
Affiliations

Affiliation

  • 1 Natural Products Research Unit, Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand.
PMID: 31177846 DOI: 10.1080/14786419.2019.1627352
Abstract

An unusual, new anthracene natural product named filamentos A (1), two new anthraquinone derivatives named filamentos B (2) and C (3), together with sixteen known compounds (4-19), were isolated from the roots of the tree Prismatomeris filamentosa. Their structures were identified by analysis of mass and spectroscopic data (IR, 1D and 2D NMR). Twelve metabolites (1-6, 9, 12-14, 16-17) showed moderate Antibacterial activities against a wide range of Gram-positive and Gram-negative bacteria such as B. subtilis, B. cereus, S. aureus, E. coli, P. aeruginosa and S. sonnei.

Keywords

Prismatomeris filamentosa; anthracene; anthraquinone; antibacterial.

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