Cell invasion is the ability of cells to migrate from one area to another via the extracellular matrix. Cell invasion is the response of normal and cancer cells to chemical and mechanical stimuli. Before migrating to a new region, the extracellular matrix is degraded by proteases within the cell. Cell invasion often occurs during wound repair, vascularization and inflammation, abnormal tissue invasion, and tumor cell metastasis.
Cell Invasion Assay
Cell invasion refers to cells crossing the basement membrane and stroma between tissues or cells and participating in physiological processes such as cell migration, tissue development and tumor metastasis. This process involves proteolysis, extracellular matrix attachment, and cell movement. Research on cell invasion often uses techniques such as Transwell assay, Boyden chamber and basement membrane model to evaluate cell invasion ability and help reveal disease development and treatment strategies.
Related Experimental Schemes
