Calcitonin/CALCA Protein, Human (HEK293, N-His)

Calcitonin, encoded by the CALCA gene, induces a swift yet transient reduction in blood calcium and phosphate levels by facilitating the incorporation of these ions into the bones. This physiological response highlights Calcitonin's role in regulating mineral homeostasis and underscores its impact on skeletal dynamics. Additionally, Katacalcin, a peptide derived from the same gene, emerges as a potent factor in lowering plasma calcium levels, further emphasizing the multifaceted influence of Calcitonin in orchestrating calcium metabolism. Calcitonin/CALCA Protein, Human (HEK293, N-His) is the recombinant human-derived Calcitonin/CALCA protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Calcitonin/CALCA Protein, Human (HEK293, N-His) is 116 a.a., with molecular weight of ~16.28 kDa.

Calcitonin, encoded by the CALCA gene, induces a swift yet transient reduction in blood calcium and phosphate levels by facilitating the incorporation of these ions into the bones. This physiological response highlights Calcitonin's role in regulating mineral homeostasis and underscores its impact on skeletal dynamics. Additionally, Katacalcin, a peptide derived from the same gene, emerges as a potent factor in lowering plasma calcium levels, further emphasizing the multifaceted influence of Calcitonin in orchestrating calcium metabolism.

Human

HEK293

C-6*His

P01258 (A26-N141)

796  [NCBI]

APFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAPGKKRDMSSDLERDHRPHVSMPQNAN

Approximately 16.28 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.