2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. FGF Family
  5. Fibroblast Growth Factor
  6. FGF-6
  7. FGF-6 Protein, Human (His)

FGF-6 Protein, Human (His)

Cat. No.: HY-P7174A
Handling Instructions

FGF-6 Protein, Human is a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells.

For research use only. We do not sell to patients.

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  • Biological Activity

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Description

FGF-6 Protein, Human is a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells.
Background

Fibroblast growth factor 6 (FGF-6) is a heparin-binding member of the FGF family, which are regulators of cell proliferation, differentiation, and function. FGF-6 binds and signals through the FGF receptors 1c, 2c, and 4[1]. FGF-6 is a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells.
Species

Human
Source

E. coli
Tag

C-6*His
Accession

P10767 (G41-I208)
Gene ID
Molecular Construction
N-term
FGF-6 (G41-I208)
Accession # P10767
6*His
C-term
Synonyms
rHuFGF-6; HBGF-6; HST-2; HSTF-2
AA Sequence

GTRANNTLLDSRGWGTLLSRSRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI

Molecular Weight

18-19 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1.0 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

FGF-6 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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