2. Recombinant Proteins
  3. Receptor Proteins
  4. G-Protein-Coupled Receptors (GPCRs)
  5. Glucagon Receptor
  6. GLP2R Protein, Human (Cell-Free, His)

GLP2R Protein, Human (Cell-Free, His)

Cat. No.: HY-P702288
Handling Instructions

GLP2R protein, a receptor for glucagon-like peptide 2 (GLP-2), operates through G proteins that activate adenylyl cyclase. It plays a crucial role in transducing the signaling effects of GLP-2, impacting physiological processes such as intestinal growth and nutrient absorption. GLP2R Protein, Human (Cell-Free, His) is the recombinant human-derived GLP2R protein, expressed by E. coli Cell-free , with N-6*His labeled tag. The total length of GLP2R Protein, Human (Cell-Free, His) is 553 a.a., with molecular weight of 64.0 kDa.

For research use only. We do not sell to patients.

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Description

GLP2R protein, a receptor for glucagon-like peptide 2 (GLP-2), operates through G proteins that activate adenylyl cyclase. It plays a crucial role in transducing the signaling effects of GLP-2, impacting physiological processes such as intestinal growth and nutrient absorption. GLP2R Protein, Human (Cell-Free, His) is the recombinant human-derived GLP2R protein, expressed by E. coli Cell-free , with N-6*His labeled tag. The total length of GLP2R Protein, Human (Cell-Free, His) is 553 a.a., with molecular weight of 64.0 kDa.
Background

The GLP2R protein functions as a receptor for glucagon-like peptide 2 (GLP-2). Its activity is mediated by G proteins, specifically those that activate adenylyl cyclase. As a receptor for GLP-2, it plays a role in transducing the signaling effects of this peptide, which is involved in various physiological processes, including the regulation of intestinal growth and nutrient absorption.
Species

Human
Source

E. coli Cell-free
Tag

N-6*His
Accession

O95838 (M1-I553)
Gene ID

9340
Molecular Construction
N-term
6*His
GLP2R (M1-I553)
Accession # O95838
C-term
Synonyms
Glucagon-like peptide 2 receptor; GLP-2 receptor; GLP-2-R; GLP-2R
AA Sequence

MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI

Molecular Weight

64.0 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

GLP2R Protein, Human (Cell-Free, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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