1. Recombinant Proteins
  2. Receptor Proteins
  3. G-Protein-Coupled Receptors (GPCRs)
  4. GPR157 Protein, Human (Cell-Free, His)

GPR157 Protein, Human (Cell-Free, His)

Cat. No.: HY-P702305
Handling Instructions

GPR157 Protein, an orphan receptor, crucially regulates neuronal differentiation in radial glial progenitors (RGPs). Its function relies on a G(q)-protein, activating a phosphatidylinositol-calcium second messenger to orchestrate intricate signaling pathways for neuronal differentiation. GPR157 Protein, Human (Cell-Free, His) is the recombinant human-derived GPR157 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of GPR157 Protein, Human (Cell-Free, His) is 335 a.a., with molecular weight of 39.4 kDa.

For research use only. We do not sell to patients.

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Description

GPR157 Protein, an orphan receptor, crucially regulates neuronal differentiation in radial glial progenitors (RGPs). Its function relies on a G(q)-protein, activating a phosphatidylinositol-calcium second messenger to orchestrate intricate signaling pathways for neuronal differentiation. GPR157 Protein, Human (Cell-Free, His) is the recombinant human-derived GPR157 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of GPR157 Protein, Human (Cell-Free, His) is 335 a.a., with molecular weight of 39.4 kDa.

Background

GPR157 Protein, an orphan receptor, serves as a key regulator in the promotion of neuronal differentiation within radial glial progenitors (RGPs). Its functional role is facilitated by a G(q)-protein, which, in turn, activates a phosphatidylinositol-calcium second messenger, orchestrating the intricate signaling pathways involved in the process of neuronal differentiation.

Species

Human

Source

E. coli Cell-free

Tag

N-10*His

Accession

Q5UAW9 (M1-T335)

Gene ID

80045

Molecular Construction
N-term
10*His
GPR157 (M1-T335)
Accession # Q5UAW9
C-term
Synonyms
G-protein coupled receptor 157
AA Sequence

MQPSPPPTELVPSERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQNFAGPSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVRAARGPRTDRLLWAFHVVSWGVPLVITVAAVALKKIGYDASDVSVGWCWIDLEAKDHVLWMLLTGKLWEMLAYVLLPLLYLLVRKHINRAHTALSEYRPILSQEHRLLRHSSMADKKLVLIPLIFIGLRVWSTVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCCSSQPPTKSPAGTPKAPAPSKPGESQESQGTPGELPST

Molecular Weight

39.4 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

GPR157 Protein, Human (Cell-Free, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
GPR157 Protein, Human (Cell-Free, His)
Cat. No.:
HY-P702305
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