2. Recombinant Proteins
  3. Receptor Proteins
  4. G-Protein-Coupled Receptors (GPCRs)
  5. GPR87 Protein, Human (Cell-Free, Strep)

GPR87 Protein, Human (Cell-Free, Strep)

Cat. No.: HY-P702309
Handling Instructions

GPR87, a lysophosphatidic acid (LPA) receptor, crucially activates p53/TP53-dependent survival pathways in response to DNA damage. Its interaction with LPA plays a key role in mediating cellular responses to DNA damage, highlighting its significance in cell survival and DNA damage repair processes. GPR87 Protein, Human (Cell-Free, Strep) is the recombinant human-derived GPR87 protein, expressed by E. coli Cell-free , with C-Twin-Strep labeled tag. The total length of GPR87 Protein, Human (Cell-Free, Strep) is 358 a.a., with molecular weight of 44.5 kDa.

For research use only. We do not sell to patients.

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Description

GPR87, a lysophosphatidic acid (LPA) receptor, crucially activates p53/TP53-dependent survival pathways in response to DNA damage. Its interaction with LPA plays a key role in mediating cellular responses to DNA damage, highlighting its significance in cell survival and DNA damage repair processes. GPR87 Protein, Human (Cell-Free, Strep) is the recombinant human-derived GPR87 protein, expressed by E. coli Cell-free , with C-Twin-Strep labeled tag. The total length of GPR87 Protein, Human (Cell-Free, Strep) is 358 a.a., with molecular weight of 44.5 kDa.
Background

GPR87, serving as a receptor for lysophosphatidic acid (LPA), plays a crucial role in p53/TP53-dependent survival pathways activated in response to DNA damage. The receptor's engagement with LPA is instrumental in mediating cellular responses to DNA damage, emphasizing its significance in processes related to cell survival and DNA damage repair.
Species

Human
Source

E. coli Cell-free
Tag

C-Twin-Strep
Accession

Q9BY21 (M1-V358)
Gene ID

53836
Molecular Construction
N-term
GPR87 (M1-V358)
Accession # Q9BY21
Twin-Strep
C-term
Synonyms
G-protein coupled receptor 87; G-protein coupled receptor 95
AA Sequence

MGFNLTLAKLPNNELHGQESHNSGNRSDGPGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWHTAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV

Molecular Weight

44.5 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

GPR87 Protein, Human (Cell-Free, Strep) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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