HAPLN1 Protein, Human (HEK293, His)

HAPLN1 protein is vital in stabilizing proteoglycan monomer aggregates in cartilage's extracellular matrix. Through interaction with hyaluronic acid, it ensures structural integrity and stability, facilitating proteoglycan binding and organization. HAPLN1's role is crucial for maintaining the extracellular environment, providing proper support and resilience in cartilage tissues. HAPLN1 Protein, Human (HEK293, His) is the recombinant human-derived HAPLN1 protein, expressed by HEK293 , with C-His labeled tag. The total length of HAPLN1 Protein, Human (HEK293, His) is 339 a.a., with molecular weight of ~52 KDa.

Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) protein plays a crucial role in stabilizing the aggregates formed by proteoglycan monomers in the extracellular matrix of cartilage, primarily through its interaction with hyaluronic acid. This function is essential for the structural integrity and stability of the cartilage matrix. By facilitating the binding and organization of proteoglycans with hyaluronic acid, HAPLN1 contributes to the maintenance of the extracellular environment, ensuring proper support and resilience within cartilage tissues.

Human

HEK293

C-His

P10915 (D16-N354)

1404  [NCBI]

Approximately 52 kDa.

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.