Hemagglutinin neuraminidase/HN Protein, HPIV-1 (Cell-Free, His)

The Hemagglutinin neuraminidase/HN protein initiates infection by attaching the virus to sialic acid-containing cell receptors. Upon binding, HN protein induces a conformational change, triggering fusion between virion and cell membranes by the F protein. HN's neuraminidase activity ensures efficient virus spread by dissociating mature virions from neuraminic acid-containing glycoproteins. Hemagglutinin neuraminidase/HN Protein, HPIV-1 (Cell-Free, His) is the recombinant Virus-derived Hemagglutinin neuraminidase/HN protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of Hemagglutinin neuraminidase/HN Protein, HPIV-1 (Cell-Free, His) is 575 a.a., with molecular weight of 65.5 kDa.

The Hemagglutinin neuraminidase/HN protein plays a crucial role in initiating infection by attaching the virus to sialic acid-containing cell receptors. Upon binding to the receptor, HN protein induces a conformational change that facilitates the triggering of fusion between virion and cell membranes by the F protein. Additionally, the neuraminidase activity of HN ensures the efficient spread of the virus by dissociating mature virions from neuraminic acid-containing glycoproteins.

Virus

E. coli Cell-free

N-10*His

P16071 (M1-S575)

/

MAEKGKTNSSYWSTTRNDNSTVNTYIDTPAGKTHIWLLIATTMHTILSFIIMILCIDLIIKQDTCMKTNIMTVSSMNESAKTIKETITELIRQEVISRTINIQSSVQSGIPILLNKQSRDLTQLIEKSCNRQELAQICENTIAIHHADGISPLDPHDFWRCPVGEPLLSNNPNISLLPGPSLLSGSTTISGCVRLPSLSIGDAIYAYSSNLITQGCADIGKSYQVLQLGYISLNSDMYPDLKPVISHTYDINDNRKSCSVIAAGTRGYQLCSLPTVNETTDYSSEGIEDLVFDILDLKGKTKSHRYKNEDITFDHPFSAMYPSVGSGIKIENTLIFLGYGGLTTPLQGDTKCVTNRCANVNQSVCNDALKITWLKKRQVVNVLIRINNYLSDRPKIVVETIPITQNYLGAEGRLLKLGKKIYIYTRSSGWHSHLQIGSLDINNPMTIKWAPHEVLSRPGNQDCNWYNRCPRECISGVYTDAYPLSPDAVNVATTTLYANTSRVNPTIMYSNTSEIINMLRLKNVQLEAAYTTTSCITHFGKGYCFHIVEINQTSLNTLQPMLFKTSIPKICKITS

65.5 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.