HSD17B13 Protein, Human (P.pastoris, His-Myc)

HSD17B13 Protein plays a pivotal role in hepatic lipid metabolism, actively contributing to the oxidation of diverse lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4. Demonstrating versatile catalytic activity in vitro, HSD17B13, notably, exhibits retinol/retinal dehydrogenase activity, emphasizing its potential impact on crucial pathways associated with lipid processing and metabolism. HSD17B13 Protein, Human (P.pastoris, His-Myc) is the recombinant human-derived HSD17B13 protein, expressed by P. pastoris , with N-His, C-Myc labeled tag. The total length of HSD17B13 Protein, Human (P.pastoris, His-Myc) is 281 a.a., with molecular weight of ~34.8 kDa.

HSD17B13 assumes a pivotal role in hepatic lipid metabolism, contributing significantly to the oxidation of diverse lipid substrates such as 17beta-estradiol, retinol, retinal, and leukotriene B4. This enzyme's catalytic activity has been demonstrated in vitro, showcasing its versatile involvement in lipid metabolism. Notably, HSD17B13 exhibits retinol/retinal dehydrogenase activity in vitro, underscoring its potential impact on critical pathways associated with lipid processing and metabolism.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

P. pastoris

N-His;C-Myc

Q7Z5P4 (20E-300K)

345275  [NCBI]

ESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQFEAVVGHKIKMK

Approximately 34.8 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized after extensive dialysis against solution in 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0 or 20 mM HEPES, 100 mM NaCl, 6% Trehalose, pH 7.5.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.