HTR7 Protein, Human (Cell-Free, His)

The HTR7 protein is a serotonin receptor that coordinates the activity of adenylyl cyclase by activating its G protein. This highlights the critical role of HTR7 in transducing signals initiated by serotonin, affecting multiple physiological processes regulated by the cyclic AMP signaling pathway. HTR7 Protein, Human (Cell-Free, His) is the recombinant human-derived HTR7 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of HTR7 Protein, Human (Cell-Free, His) is 479 a.a., with molecular weight of 56.4 kDa.

The HTR7 protein represents one of the various receptors for 5-hydroxytryptamine (serotonin), a multifunctional biogenic hormone acting as a neurotransmitter, hormone, and mitogen. The receptor's activity is orchestrated through G proteins, specifically those that activate adenylate cyclase. This highlights the pivotal role of HTR7 in transducing signals initiated by serotonin, emphasizing its involvement in diverse physiological processes regulated by cyclic AMP signaling pathways. The interaction with serotonin and subsequent activation of adenylate cyclase underscore HTR7's significance in mediating cellular responses to this crucial neurotransmitter and hormone, contributing to the broader understanding of serotonin's effects in various biological contexts.

Human

E. coli Cell-free

N-10*His

P34969 (M1-D479)

3363

MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD

56.4 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.