P2RY12 Protein, Mouse (Cell-Free, His)

P2RY12 protein is a receptor for ADP and ATP and inhibits adenylyl cyclase second messenger system through G protein. P2RY12 is critical for normal platelet aggregation and coagulation, where it mediates responses to nucleotide signals. P2RY12 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived P2RY12 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of P2RY12 Protein, Mouse (Cell-Free, His) is 347 a.a., with molecular weight of 45.5 kDa.

P2RY12 Protein, identified as a receptor for ADP and ATP, operates through G-proteins to inhibit the adenylyl cyclase second messenger system. Essential for normal platelet aggregation and blood coagulation, P2RY12 plays a crucial role in mediating responses to nucleotide signals involved in these processes. Through its receptor function, it serves as a key regulator in platelet activation, contributing to the intricate machinery of hemostasis and coagulation. The inhibition of the adenylyl cyclase second messenger system by P2RY12 underscores its significance in orchestrating cellular responses and highlights its potential as a therapeutic target for modulating platelet function and blood clotting.

Mouse

E. coli Cell-free

N-10*His

Q9CPV9 (M1-M347)

70839

MDVPGVNTTSANTTFSPGTSTLCVRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGPLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVVIWAFMFLISLPNMILTNRRPKDKDVTKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKVPKKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCSAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLTSMLRCSNSTSTSGTNKKKGQEGGEPSEETPM

45.5 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.